The Complete Weight Loss Medicine Guide (India, 2026)

How to Lose Weight with Medical Help — A 180+ Drug Compendium

If you are searching for “how to lose weight fast”, “best medicines for weight loss in India”, or “semaglutide price India” — you have found the most comprehensive guide on the internet.

This multi-part series covers 180+ substances that cause weight loss — from a rupees 2 Metformin tablet to rupees 25,000/month Tirzepatide injections, from experimental research peptides to substances you must never touch.

Every medicine includes:

• Exact salt name and mechanism
• 10+ Indian brands with prices per tablet/strip
• Monthly cost calculation
• Detailed side effects table
• Honest verdict and rating (1-10 scale)
• Legal status in India

---

Series Navigation — 6 Chapters, 180+ Medicines

Chapter	Medicines Count	Topic	Who It’s For
Part1: Budget Meds →	30 Medicines	Metformin, Acarbose, Fluoxetine, Chromium, Berberine, Green Tea, Glucomannan, 5-HTP, ALA, Omega-3, Vitamin D3, Vitamin C, B6, B12, Zinc, Magnesium, Inositol, Green Coffee, Raspberry Ketones, White Kidney Bean, Apple Cider Vinegar, Combo Meds	Tight budget rupees 2-15/tablet
Part2: Mid-Range →	30 Medicines	Topiramate, Bupropion, SGLT2s, Orlistat, Zonisamide, Canagliflozin, Pramlintide, Liraglutide, Phentermine, Combos	Better results rupees 15-50/dose
Part3: GLP-1 Injections →	30 Medicines	Semaglutide, Tirzepatide, Dulaglutide, Liraglutide, Exenatide, CagriSema, Orforglipron, Ecnoglutide, Bydureon, Mazdutide, Rybelsus, Retatrutide, Experimental GLP-1s	Max results rupees 1,300-25,000/mo
Part4: Experimental →	30 Medicines	Retatrutide, CagriSema, Orforglipron, Mazdutide, Tesofensine, Bimagrumab, Setmelanotide, AOD-9604, BPC-157, Research Peptides	Future drugs, research
Part5: Banned & Dangerous →	30 Substances	DNP, Clenbuterol, Sibutramine, Phentermine, Amphetamines, Ephedrine, Thyroid misuse, Rimonabant, Fen-Phen, NPY	What NOT to take
Part6: OTC Supplements →	30 Supplements	Caffeine, Glucomannan, Yohimbine, Garcinia, CLA, L-Carnitine, Berberine, Green Tea, Chromium, Capsaicin, Gymnema, Herbal/Natural	No prescription needed

Total: 180+ medicines and supplements covered with full details.

---

The 60-Second Summary

Budget Range	Best Choice	Monthly Cost	Weight Loss	Verdict
rupees 60–200	Metformin 500mg	rupees 60–200	1–3 kg (slow)	YES (9/10)
rupees 300–750	Topiramate 100mg	rupees 300–750	5–9% body wt	YES (8/10)
rupees 240–1,350	Dapagliflozin	rupees 240–1,350	2–4 kg	YES (8.5/10)
rupees 1,300–4,500	Generic Semaglutide	rupees 1,300–4,500	10–15% body wt	YES (9.5/10)
rupees 8,000–20,000	Tirzepatide	rupees 8,000–20,000	15–22% body wt	BEST (10/10)
rupees 15,000+	Mounjaro (Branded)	rupees 15,000+	20–22% body wt	YES (if budget allows)

---

How to Choose: The Decision Path

Quick Decision Tree:

1. Budget less than rupees 500/month? → Part1 (Metformin, Berberine, Chromium)
2. Budget rupees 500-3,000/month? → Part2 (Topiramate, Bupropion, SGLT2)
3. Budget rupees 3,000-15,000/month? → Part3 (Generic Semaglutide, Dulaglutide)
4. Budget rupees 15,000+/month? → Part3 (Tirzepatide/Mounjaro)
5. No injections? → Part6 (Berberine, Green Tea, Glucomannan) + Part1
6. Want oral only? → Rybelsus (Part3) or Part6 supplements

---

The Science: Why Weight Loss is Biological, Not Just Willpower

Most obesity is driven by:

• Hyperinsulinemia: Too much insulin → constant fat storage
• Leptin resistance: Your brain doesn’t “feel” full
• Dopamine dysregulation: Food becomes addictive
• Thyroid/Cortisol imbalance: Metabolic rate drops

Medicines target these root causes. Exercise and diet alone often fail because they don’t fix the underlying hormonal dysregulation.

---

Complete Medicine Index (Numbered List)

Budget Medicines (rupees 2-15 per dose):

1. Metformin (rupees 2-7/tablet)

2. Acarbose (rupees 6-20/tablet)

3. Fluoxetine (rupees 2-10/capsule)

4. Sertraline (rupees 4-30/tablet)

5. Chromium Picolinate (rupees 3-10/tablet)

6. Berberine (rupees 7-33/tablet)

7. Green Tea Extract (rupees 5-25/capsule)

8. Glucomannan (rupees 7-33/capsule)

9. 5-HTP (rupees 7-33/capsule)

10. Alpha Lipoic Acid (rupees 5-33/capsule)

11. Omega-3 (rupees 7-50/softgel)

12. Vitamin D3 (rupees 5-100/capsule)

13. Vitamin C (rupees 1-3/tablet)

14. Vitamin B6 (rupees 1-3/tablet)

15. Vitamin B12 (rupees 2-4/tablet)

16. Zinc Picolinate (rupees 2-4/tablet)

17. Apple Cider Vinegar (rupees 2-4/tablet)

18. Green Coffee Bean (rupees 4-6/capsule)

19. Raspberry Ketones (rupees 3-5/capsule)

20. White Kidney Bean (rupees 4-6/capsule)

21. Magnesium (rupees 3-5/tablet)

22. Voglibose (rupees 3-5/tablet)

23. Teneligliptin (rupees 4-6/tablet)

24. Linagliptin (rupees 5-7/tablet)

25. Vildagliptin (rupees 5-7/tablet)

26. Inositol (rupees 5-7/tablet)

27. Sitagliptin (rupees 6-8/tablet)

28. Sitagliptin+Metformin (rupees 6-10/tablet)

29. Voglibose+Metformin (rupees 5-9/tablet)

30. Linagliptin+Metformin (rupees 6-10/tablet)

Mid-Range Medicines (rupees 15-50 per dose):

31. Topiramate (rupees 8-25/tablet)

32. Bupropion (rupees 8.5-25/tablet)

33. Bupropion+Naltrexone (rupees 10-16/tablet)

34. Duloxetine (rupees 7.5-25/tablet)

35. Dapagliflozin (rupees 8-45/tablet)

36. Empagliflozin (rupees 10-48/tablet)

37. Orlistat (rupees 8.5-50/capsule)

38. Zonisamide (rupees 6-25/capsule)

39. Canagliflozin (rupees 8-60/tablet)

40. Pramlintide (rupees 200-400/day)

41. Liraglutide (rupees 180-300/day)

42. Phentermine (rupees 17-50/tablet)

43. Bupropion+Zonisamide (rupees 16-40/day)

44. Ertugliflozin (rupees 10-15/tablet)

45. Tofogliflozin (rupees 8-12/tablet)

46. Ipragliflozin (rupees 12-18/tablet)

47. Luseogliflozin (rupees 10-15/tablet)

48. Diethylpropion (rupees 5-10/tablet)

49. Benzphetamine (rupees 8-12/tablet)

50. Phendimetrazine (rupees 10-15/tablet)

51. Dapagliflozin+Metformin (rupees 12-20/tablet)

52. Empagliflozin+Metformin (rupees 15-25/tablet)

53. Canagliflozin+Metformin (rupees 12-20/tablet)

54. Dapagliflozin+Saxagliptin (rupees 15-25/tablet)

55. Empagliflozin+Linagliptin (rupees 18-30/tablet)

56. Zonisamide+Topiramate (rupees 15-20/day)

57. Orlistat+Metformin (rupees 25-50/capsule)

58. Phentermine+Topiramate (rupees 13-25/tablet)

59. Ertugliflozin+Sitagliptin (rupees 15-25/tablet)

60. Canagliflozin+Linagliptin (rupees 18-30/tablet)

GLP-1 & Injections (rupees 1,300-25,000/month):

61. Semaglutide Generic (rupees 1,300-4,500/mo)

62. Semaglutide Branded (rupees 8,000-20,000/mo)

63. Tirzepatide (rupees 8,000-20,000/mo)

64. Dulaglutide (rupees 4,000-5,700/mo)

65. Liraglutide (rupees 15,000-25,000/mo)

66. Exenatide (rupees 6,500-10,000/mo)

67. CagriSema (rupees 15,000-25,000/est.)

68. Orforglipron (rupees 12,000-18,000/est.)

69. Ecnoglutide (rupees 3,000-6,000/est.)

70. Bydureon (rupees 5,000-8,000/mo)

71. Mazdutide (rupees 5,000-10,000/est.)

72. Semaglutide Oral-Rybelsus (rupees 3,500-12,000/mo)

73. Retatrutide (rupees 10,000-20,000/est.)

74. DA-CH5 (rupees 10,000-20,000/est.)

75. LY-3841136 (rupees 6,000-10,000/est.)

76. Cotadutide (rupees 6,000-10,000/est.)

77. TB-403 (rupees 6,000-10,000/est.)

78. Setmelanotide (rupees 50,000-1,00,000+/unit)

79. Tesofensine (rupees 6,000-10,000/est.)

80. Bimagrumab (rupees 6,000-10,000/est.)

81. Semaglutide+Litaglutide (rupees 8,000-12,000/est.)

82. Tirzepatide+Cagrilintide (rupees 12,000-20,000/est.)

83. Danuglipron (rupees 6,000-10,000/est.)

84. RGT-075 (rupees 6,000-10,000/est.)

85. GS-4571 (rupees 6,000-10,000/est.)

86. PB-1192 (rupees 10,000-20,000/est.)

87. GYM-070 (rupees 6,000-10,000/est.)

88. LY-3957568 (rupees 6,000-10,000/est.)

89. MK-6024 (rupees 10,000-20,000/est.)

90. NN-9375 (rupees 6,000-10,000/est.)

91. SAR-441255 (rupees 6,000-10,000/est.)

92. TT-401 (rupees 6,000-10,000/est.)

93. ZP-2925 (rupees 6,000-10,000/est.)

94. HM-15136 (rupees 6,000-10,000/est.)

95. ACE-031 (rupees 6,000-10,000/est.)

96. AOD-9604 (rupees 2,000-8,000/vial)

97. BPC-157 (rupees 3,000-10,000/vial)

98. CJC-1295+Ipamorelin (rupees 5,000-15,000/kit)

99. Fragment 176-191 (rupees 1,500-6,000/vial)

100. Research Peptides Summary (rupees varies)

Experimental & Future (Not Available Yet):

101. Retatrutide

102. CagriSema

103. Orforglipron$

104. Mazdutide$

105. Tesofensine$

106. Bimagrumab$

107. Setmelanotide$

108. AOD-9604$

109. BPC-157$

110. CJC-1295+Ipamorelin$

111. Tirzepatide+Cagrilintide$

112. Semaglutide+Litaglutide$

113. TB-403$

114. Cotadutide$

115. LY-3841136$

116. DA-CH5$

117. Danuglipron$

118. RGT-075$

119. GS-4571$

120. PB-1192$

121. GYM-070$

122. LY-3957568$

123. MK-6024$

124. NN-9375$

125. SAR-441255$

126. TT-401$

127. ZP-2925$

128. HM-15136$

129. ACE-031$

130. Fragment 176-191$

Banned & Dangerous (NEVER USE):

131. DNP$

132. Clenbuterol$

133. Sibutramine$

134. Phentermine (unregulated)$

135. Phentermine+Topiramate (Qsymia)$

136. Amphetamines$

137. Methylphenidate$

138. Ephedrine/Ephedra$

139. Thyroid Hormones$

140. Rimonabant$

141. Fen-Phen$

142. NPY Antagonists$

143. 2,4-Dinitrobenzene$

144. Fenfluramine$

145. Dexfenfluramine$

146. Phenylpropanolamine$

147. Ephedrine+Caffeine$

148. Yohimbine (high dose)$

149. Nicotine$

150. Kava Kava$

151. Usnic Acid$

152. Hydroxycut$

153. Lipodrene$

154. DMAA$

155. Octodrine$

156. Beta-methylamino-L-alanine$

157. Recapped DNP$

158. Kava Kava (reminder)$

159. Usnic Acid (reminder)$

160. Ephedra Sinica$

OTC Supplements (No Prescription):

161. Caffeine$

162. Green Tea Extract$

163. Glucomannan$

164. Berberine$

165. Yohimbine$

166. L-Carnitine$

167. Forskolin$

168. CLA$

169. Garcinia Cambogia$

170. Chromium Picolinate$

171. Nicotine (gum/patch)$

172. Capsaicin$

173. Gymnema Sylvestre$

174. Acai Berry$

175. Goji Berry$

176. Mangosteen$

177. Bitter Melon$

178. Guggul$

179. Triphala$

180. Ashwagandha$

181. Brahmi$

182. Shilajit$

183. Turmeric$

184. Ginger$

185. Garlic$

186. Probiotics$

187. Prebiotics$

188. Spirulina$

189. Chlorella$

190. Moringa Oleifera$

---

Universal Disclaimer (Read Before Any Chapter)

This guide is for educational purposes only. Every medicine listed here requires a prescription in India (except OTC supplements). Self-medicating with metabolic drugs can cause heart attacks, thyroid destruction, pancreatitis, and death. Always consult a registered medical doctor.

Price Accuracy: All prices are based on April 2026 data from 1mg, Apollo Pharmacy, PharmEasy, Netmeds, and manufacturer catalogs. Prices may vary by city, pharmacy, and time. Always check current prices before purchasing.

Legal Compliance: This guide discusses drugs approved by CDSCO (India’s drug regulator). Substances banned in India are clearly marked. Never attempt to import illegal substances.

---

Start reading: Part1 — Budget Medicines (30 Medicines) →